PDCD10 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728460

Produktdetails

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PDCD10 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PDCD10 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Andere Bezeichnung: Pdcd10 (PDCD10 Produkte)

Synonyme: CCM3 Protein, TFAR15 Protein, 2410003B13Rik Protein, Ccm3 Protein, Tfa15 Protein, Tfar15 Protein, zgc:85629 Protein, ccm3a Protein, pdcd10 Protein, zgc:65826 Protein, programmed cell death 10 Protein, programmed cell death 10 S homeolog Protein, programmed cell death 10b Protein, programmed cell death 10a Protein, PDCD10 Protein, Pdcd10 Protein, pdcd10.S Protein, pdcd10b Protein, pdcd10a Protein

Hintergrund: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molekulargewicht: 24.5 kDa

NCBI Accession: NP_009148