PCK1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728410

Produktdetails

Target: PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PCK1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PCK1 / PEPCK1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))

Andere Bezeichnung: Pck1,pepck1 (PCK1 Produkte)

Synonyme: PEPCK-C Protein, PEPCK1 Protein, PEPCKC Protein, PEPCK Protein, PEPCK-M Protein, PEPCK2 Protein, 1810010O14Rik Protein, 9130022B02Rik Protein, cb856 Protein, cb924 Protein, fj93h11 Protein, zgc:63869 Protein, wu:fc51c05 Protein, wu:fj93h11 Protein, pepck-c Protein, pepck1 Protein, pepckc Protein, PCK1 Protein, PPCK1 Protein, AI265463 Protein, Pck-1 Protein, GTP Protein, PCK Protein, Pepck Protein, RATPEPCK Protein, Ppc1C Protein, PHOSPHOENOLPYRUVATE CARBOXYKINASE Protein, T28I19.150 Protein, T28I19_150 Protein, phosphoenolpyruvate carboxykinase 1 Protein, 143299_at Protein, CG10924 Protein, CG17725 Protein, Dmel\\CG17725 Protein, Dromel_CG17725_FBtr0086701_pepck_mORF Protein, dPEPCK Protein, pepck Protein, PEPC Protein, PEPCase Protein, ppc Protein, phosphoenolpyruvate carboxykinase 1 Protein, phosphoenolpyruvate carboxykinase 2, mitochondrial Protein, phosphoenolpyruvate carboxykinase 2 (mitochondrial) Protein, phosphoenolpyruvate carboxykinase 1 (soluble) Protein, phosphoenolpyruvate carboxykinase 1 S homeolog Protein, phosphoenolpyruvate carboxykinase, cytosolic [GTP] Protein, phosphoenolpyruvate carboxykinase 1, cytosolic Protein, phosphoenolpyruvate carboxylase 7 Protein, Phosphoenolpyruvate carboxykinase Protein, phosphoenolpyruvate carboxylase Protein, PCK1 Protein, PCK2 Protein, Pck2 Protein, pck1 Protein, pck1.S Protein, LOC100634531 Protein, Pck1 Protein, pep7 Protein, Pepck Protein, LOC107777405 Protein

Hintergrund: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

Molekulargewicht: 69 kDa

NCBI Accession: NP_002582

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis