Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Osteoprotegerin Protein

TNFRSF11B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, PI, AbP, STD Active
Produktnummer ABIN2728025
  • Target Alle Osteoprotegerin (TNFRSF11B) Proteine anzeigen
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 17
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Quelle
    • 12
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func), Protein Interaction (PI), Antibody Production (AbP), Standard (STD)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human Osteoprotegerin / TNFRSF11B protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its ability to neutralize the stimulation of U937 cells treated with 10 ng/ml of soluble RANKL (sRANKL).
    Top Product
    Discover our top product TNFRSF11B Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handhabung
    Resuspend the protein in the desired concentration in proper buffer
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Andere Bezeichnung
    Osteoprotegerin,tnfrsf11b (TNFRSF11B Produkte)
    Synonyme
    CD254 Protein, ODF Protein, OPGL Protein, OPTB2 Protein, RANKL Protein, TRANCE Protein, hRANKL2 Protein, sOdf Protein, OCIF Protein, OPG Protein, TR1 Protein, Opg Protein, ocif Protein, opg Protein, tr1 Protein, TNF superfamily member 11 Protein, TNF receptor superfamily member 11b Protein, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Protein, TNF receptor superfamily member 11B Protein, tumor necrosis factor receptor superfamily member 11b S homeolog Protein, tumor necrosis factor receptor superfamily, member 11b Protein, TNFSF11 Protein, TNFRSF11B Protein, Tnfrsf11b Protein, tnfrsf11b.S Protein
    Substanzklasse
    Chemical
    Hintergrund
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
    Molekulargewicht
    20 kDa
    NCBI Accession
    NP_002537
Sie sind hier:
Kundenservice