NACA Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2726835

Produktdetails

Target: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NACA Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Andere Bezeichnung: Nascent Polypeptide-Associated Complex alpha Subunit (Naca) (NACa1 Produkte)

Synonyme: AL022831 Protein, AL024382 Protein, Gm1878 Protein, mKIAA0363 Protein, skNAC Protein, ik:tdsubc_2b5 Protein, nkn Protein, tdsubc_2b5 Protein, xx:tdsubc_2b5 Protein, NACA1 Protein, nascent polypeptide-associated complex alpha polypeptide Protein, nascent polypeptide-associated complex alpha subunit Protein, Naca Protein, naca Protein, NACA Protein

Hintergrund: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.

Molekulargewicht: 23.2 kDa

NCBI Accession: NP_005585

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development