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MUS81 Protein (Myc-DYKDDDDK Tag)

MUS81 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2726587
  • Target Alle MUS81 Proteine anzeigen
    MUS81 (MUS81 Endonuclease Homolog (MUS81))
    Protein-Typ
    Recombinant
    Spezies
    • 3
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses MUS81 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human MUS81 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MUS81 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MUS81 (MUS81 Endonuclease Homolog (MUS81))
    Andere Bezeichnung
    Mus81 (MUS81 Produkte)
    Synonyme
    CG3026 Protein, Dmel\\CG3026 Protein, EG:BACR7A4.16 Protein, MUS81 Protein, GB15332 Protein, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 Protein, ATMUS81 Protein, F6I18.220 Protein, F6I18_220 Protein, MMS AND UV SENSITIVE 81 Protein, SLX3 Protein, slx3 Protein, 1200008A18Rik Protein, AI182501 Protein, AW045863 Protein, wu:fc26g01 Protein, zgc:66489 Protein, zgc:91801 Protein, CG3026 gene product from transcript CG3026-RA Protein, MUS81 structure-specific endonuclease subunit Protein, crossover junction endonuclease MUS81 Protein, Restriction endonuclease, type II-like superfamily protein Protein, Mus81p Protein, Holliday junction resolvase subunit Mus81 Protein, MUS81 protein Protein, hypothetical protein Protein, mus81 Protein, MUS81 Protein, LOC725951 Protein, Mus81 Protein, CAALFM_C600540WA Protein
    Hintergrund
    This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after interstrand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.
    Molekulargewicht
    61 kDa
    NCBI Accession
    NP_079404
    Pathways
    DNA Reparatur
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