MTHFD1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2726507

Produktdetails

Target: MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MTHFD1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MTHFD1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

Andere Bezeichnung: Mthfd1 (MTHFD1 Produkte)

Synonyme: MTHFC Protein, MTHFD Protein, Tb07.27M11.970 Protein, Dcs Protein, E430024A07Rik Protein, Mthfd Protein, GB13160 Protein, cb325 Protein, fc29f07 Protein, mthfd1 Protein, wu:fc29f07 Protein, zgc:55597 Protein, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Protein, C-1-tetrahydrofolate synthase, cytoplasmic Protein, putative C-1-tetrahydrofolate synthase, cytoplasmic Protein, putative C-1-tetrahydrofolate synthase,cytoplasmic Protein, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Protein, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Protein, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b Protein, c-1-tetrahydrofolate synthase, cytoplasmic Protein, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog Protein, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase Protein, MTHFD1 Protein, Mthfd1 Protein, Tc00.1047053509509.20 Protein, Tc00.1047053511741.50 Protein, Tc00.1047053511517.60 Protein, Tc00.1047053508207.240 Protein, Tb927.7.1600 Protein, LINJ_26_0310 Protein, LBRM_26_0350 Protein, LMJF_26_0320 Protein, mthfd1l Protein, LOC550749 Protein, mthfd1b Protein, Tsp_00651 Protein, mthfd1.L Protein, mthfd1 Protein, LOC589933 Protein, LOC100634307 Protein

Hintergrund: This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

Molekulargewicht: 101.4 kDa

NCBI Accession: NP_005947

Pathways: Methionine Biosynthetic Process