Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)

Details zu Produkt Nr. ABIN2724952, Anbieter: Anmelden zum Anzeigen
Proteinname
  • HUFI-2
  • 5133400F20Rik
  • AI850587
  • wu:fj34c02
  • zgc:113956
  • zgc:63771
  • LRR binding FLII interacting protein 2
  • leucine rich repeat (in FLII) interacting protein 2
  • leucine rich repeat (in FLII) interacting protein 2 L homeolog
  • LRRFIP2
  • Lrrfip2
  • lrrfip2
  • lrrfip2.L
Proteineigenschaft
Transcript Variant 3
2
1
1
1
1
1
Spezies
Human
2
1
1
1
1
Quelle
HEK-293 Cells
3
1
1
1
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
Dieses LRRFIP2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
Applikation
Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Spezifität Optimal preservation of protein structure, post-translational modifications and functions.
Produktmerkmale
  • Recombinant human LRRFIP2 (transcript variant 3) protein expressed in HEK293 cells.
  • Produced with end-sequenced ORF clone
Reinheit > 80 % as determined by SDS-PAGE and Coomassie blue staining
Proteinname Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2)
Hintergrund The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex.
Molekulargewicht 48.1 kDa
NCBI Accession NP_001127841
Applikations-hinweise Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays
Kommentare

The tag is located at the C-terminal.

Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration > 50 μg/mL
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Lagerung -80 °C
Informationen zur Lagerung Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Bilder des Herstellers
Western Blotting (WB) image for Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) (ABIN2724952) Validation with Western Blot
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