KMO Protein (Myc-DYKDDDDK Tag)
(1 reference)-
- Target Alle KMO Proteine anzeigen
- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses KMO Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Kynurenine 3-monooxygenase / KMO protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 39-219) protein (His-IF2DI Tag)
KMO Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-407) protein (GST tag)KMO Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-479) protein (Strep Tag)Crystallography grade KMO Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486) protein (Strep Tag)Crystallography grade KMO Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486), (full length) protein (His-SUMO Tag)KMO Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) protein (DYKDDDDK Tag)KMO Spezies: Human Wirt: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486), (full length) protein (His tag)KMO Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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-
: "Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase." in: Assay and drug development technologies, Vol. 13, Issue 8, pp. 466-75, (2015) (PubMed).
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: "Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase." in: Assay and drug development technologies, Vol. 13, Issue 8, pp. 466-75, (2015) (PubMed).
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- Target
- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
- Andere Bezeichnung
- Kynurenine 3-Monooxygenase,kmo (KMO Produkte)
- Synonyme
- AI046660 Protein, dJ317G22.1 Protein, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) Protein, kynurenine 3-monooxygenase Protein, Kmo Protein, KMO Protein
- Hintergrund
- Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. [UniProtKB/Swiss-Prot Function]
- Molekulargewicht
- 55.6 kDa
- NCBI Accession
- NP_003670
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