KCNJ6 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724044

Produktdetails

Target: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses KCNJ6 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human KCNJ6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Andere Bezeichnung: Kcnj6 (KCNJ6 Produkte)

Synonyme: kcnj6 Protein, BIR1 Protein, GIRK-2 Protein, GIRK2 Protein, KATP-2 Protein, KATP2 Protein, KCNJ7 Protein, KIR3.2 Protein, hiGIRK2 Protein, Kir3.2 Protein, weaver Protein, wv Protein, potassium voltage-gated channel subfamily J member 6 Protein, potassium channel, inwardly rectifying subfamily J, member 5 Protein, potassium inwardly-rectifying channel, subfamily J, member 6 Protein, KCNJ6 Protein, kcnj5 Protein, Kcnj6 Protein

Hintergrund: This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. [UniProtKB/Swiss-Prot Function]

Molekulargewicht: 48.3 kDa

NCBI Accession: NP_002231