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IL-31 Protein

IL31 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
Produktnummer ABIN2723702
  • Target Alle IL-31 (IL31) Proteine anzeigen
    IL-31 (IL31) (Interleukin 31 (IL31))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 12
    • 5
    • 4
    • 2
    • 1
    Human
    Quelle
    • 12
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human Interleukin-31 / IL31 protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Measured by its ability to induce STAT3 activation in human U87 cells.
    Top Product
    Discover our top product IL31 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handhabung
    Resuspend the protein in the desired concentration in proper buffer
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    IL-31 (IL31) (Interleukin 31 (IL31))
    Andere Bezeichnung
    Interleukin-31,il31 (IL31 Produkte)
    Synonyme
    IL-31 Protein, 1700013B14Rik Protein, IL31 Protein, interleukin 31 Protein, IL31 Protein, Il31 Protein
    Hintergrund
    IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008].
    Molekulargewicht
    15.8 kDa
    NCBI Accession
    NP_001014358
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