H2AFZ Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2722805

Produktdetails

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses H2AFZ Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Histone H2A.Z protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Andere Bezeichnung: Histone h2a.z (H2AFZ Produkte)

Synonyme: H2A.Z-1 Protein, H2A.z Protein, H2A/z Protein, H2AZ Protein, H2A.Z Protein, H2a.z-1 Protein, H2AFV Protein, H2Az Protein, XH2AZ Protein, h2a.zl1 Protein, h2a.zl2 Protein, H2A histone family member Z Protein, H2A histone family, member Z Protein, H2A histone family member Z L homeolog Protein, histone H2A.Z Protein, H2AFZ Protein, H2afz Protein, h2afz.L Protein

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Molekulargewicht: 13.4 kDa

NCBI Accession: NP_002097

Pathways: Telomere Maintenance