HSPH1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2722568

Produktdetails

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses HSPH1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Heat shock protein 105 / HSP105 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Berthenet, Boudesco, Collura, Svrcek, Richaud, Hammann, Causse, Yousfi, Wanherdrick, Duplomb, Duval, Garrido, Jego: "Extracellular HSP110 skews macrophage polarization in colorectal cancer." in: Oncoimmunology, Vol. 5, Issue 7, pp. e1170264, (2016) (PubMed).

Antigendetails

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Andere Bezeichnung: Heat Shock Protein 105,hsp105 (HSPH1 Produkte)

Synonyme: hsp105 Protein, hsp105a Protein, hsp105b Protein, hsp110 Protein, hsph1b Protein, Hsp105 Protein, HSP105 Protein, HSP105A Protein, HSP105B Protein, NY-CO-25 Protein, 105kDa Protein, AI790491 Protein, Hsp110 Protein, hsp-E7I Protein, hsph1 Protein, hsph1a Protein, heat shock protein family H (Hsp110) member 1 Protein, heat shock protein family H (Hsp110) member 1 S homeolog Protein, heat shock protein 105 kDa Protein, heat shock 105kDa/110kDa protein 1 Protein, heat shock protein family H (Hsp110) member 1 L homeolog Protein, hsph1 Protein, hsph1.S Protein, HSPH1 Protein, LOC100546590 Protein, Hsph1 Protein, hsph1.L Protein

Hintergrund: This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers.

Molekulargewicht: 96.7 kDa

NCBI Accession: NP_006635