GLUD1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2721997

Produktdetails

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GLUD1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Glutamate dehydrogenase 1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Andere Bezeichnung: Glutamate Dehydrogenase 1 (GLUD1 Produkte)

Synonyme: GDH Protein, gdh1 Protein, GDH 1 Protein, glud1 Protein, GLUD1 Protein, cb719 Protein, wu:fb16e02 Protein, wu:fb58f12 Protein, wu:fe37f03 Protein, wu:fj43f02 Protein, zgc:192851 Protein, zgc:55630 Protein, GDH1 Protein, GLUD Protein, AI118167 Protein, Gdh-X Protein, Glud Protein, Gludl Protein, Ac2-281 Protein, Gdh1 Protein, Gludeha Protein, MRG-2 Protein, GLUTAMATE DECARBOXYLASE 1 Protein, GLUTAMATE DEHYDROGENASE 1 Protein, MRG7.13 Protein, MRG7_13 Protein, glutamate dehydrogenase 1 Protein, C2H1orf130 Protein, legdh1 Protein, cb622 Protein, wu:fc33g09 Protein, wu:fc66a10 Protein, zgc:77186 Protein, glutamate dehydrogenase 1 Protein, glutamate dehydrogenase 1 S homeolog Protein, glutamate dehydrogenase 1, mitochondrial Protein, glutamate dehydrogenase 1b Protein, glutamate dehydrogenase Protein, non-compact myelin associated protein Protein, glutamate dehydrogenase 1a Protein, GLUD1 Protein, GDH1 Protein, glud1 Protein, glud1.S Protein, LOC693461 Protein, glud1b Protein, Glud1 Protein, HACJB3_RS00320 Protein, LOC100587725 Protein, NCMAP Protein, gdh1 Protein, glud1a Protein

Hintergrund: This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

Molekulargewicht: 56 kDa

NCBI Accession: NP_005262

Pathways: Positive Regulation of Peptide Hormone Secretion, Warburg Effekt