GCLC Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2721765

Produktdetails

Target: GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GCLC Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human GCLC / GLCLC protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

Andere Bezeichnung: Gclc,glclc (GCLC Produkte)

Synonyme: GCLC Protein, gclc Protein, MGC146287 Protein, 2259 Protein, CG2259 Protein, DmGCLC Protein, DmGCS Protein, DmGCSh Protein, Dmel\\CG2259 Protein, GCL Protein, GCLc Protein, GCSh Protein, Gcs Protein, Gcsh Protein, DDBDRAFT_0186120 Protein, DDBDRAFT_0231403 Protein, DDB_0186120 Protein, DDB_0231403 Protein, GCS Protein, GLCL Protein, GLCLC Protein, D9Wsu168e Protein, GLCL-H Protein, Ggcs-hs Protein, Glclc Protein, cb1049 Protein, fe36e11 Protein, wu:fe36e11 Protein, glutamate-cysteine ligase catalytic subunit Protein, glutamate-cysteine ligase, catalytic subunit Protein, Glutamate-cysteine ligase catalytic subunit Protein, gamma glutamylcysteine synthetase Protein, glutamate-cysteine ligase, catalytic subunit L homeolog Protein, glutamate-cysteine ligase, catalytic subunit S homeolog Protein, gamma-glutamylcysteine synthetase Protein, GCLC Protein, gclc Protein, Gclc Protein, LbGCS Protein, gcsA Protein, gclc.L Protein, gclc.S Protein, GSH1 Protein

Hintergrund: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010].

Molekulargewicht: 72.6 kDa

NCBI Accession: NP_001489

Pathways: Cell RedoxHomeostasis