CRYGD Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2721678

Produktdetails

Target: CRYGD (Crystallin, gamma D (CRYGD))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CRYGD Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Gamma-crystallin D protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CRYGD (Crystallin, gamma D (CRYGD))

Andere Bezeichnung: gamma-Crystallin D (CRYGD Produkte)

Synonyme: ccp Protein, caca Protein, cca3 Protein, cryg4 Protein, cry-g-d Protein, MGC85594 Protein, CRYGD Protein, CACA Protein, CCA3 Protein, CCP Protein, CRYG4 Protein, CTRCT4 Protein, PCC Protein, cry-g-D Protein, Aey4 Protein, Cryg-1 Protein, DGcry-1 Protein, Lop12 Protein, Cryg4 Protein, Len Protein, crystallin gamma D L homeolog Protein, crystallin gamma D Protein, crystallin, gamma D Protein, crygd.L Protein, CRYGD Protein, Crygd Protein

Hintergrund: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Molekulargewicht: 20.6 kDa

NCBI Accession: NP_008822