TNNI2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2720885

Produktdetails

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TNNI2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Fast skeletal muscle Troponin I (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Andere Bezeichnung: Fast Skeletal Muscle Troponin I (TNNI2 Produkte)

Synonyme: AMCD2B Protein, DA2B Protein, FSSV Protein, fsTnI Protein, TnI-F4 Protein, TnI Protein, TNI Protein, hm:zehn0173 Protein, tnni2 Protein, tropI-1d Protein, zgc:86800 Protein, troponin I2, fast skeletal type Protein, troponin I type 2 (skeletal, fast) Protein, troponin I, fast skeletal muscle-like Protein, troponin I, skeletal, fast 2 Protein, troponin I type 2a (skeletal, fast), tandem duplicate 4 Protein, TNNI2 Protein, Tnni2 Protein, tnni2a.4 Protein

Hintergrund: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 21.2 kDa

NCBI Accession: NP_001139301