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Ezrin Protein (EZR) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

EZR Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2720647
  • Target Alle Ezrin (EZR) Proteine anzeigen
    Ezrin (EZR)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 6
    • 1
    • 1
    • 1
    Human
    Quelle
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Ezrin Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Ezrin (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product EZR Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Sun, Wu, Cai, Wang, Liu, Blot, Shu, Cai: "A prospective study of autoantibodies to Ezrin and pancreatic cancer risk." in: Cancer causes & control : CCC, Vol. 27, Issue 6, pp. 831-5, (2016) (PubMed).

    Miyaji, Shahrizaila, Umapathi, Chan, Hirata, Yuki: "Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?" in: Human immunology, Vol. 75, Issue 11, pp. 1089-91, (2015) (PubMed).

  • Target
    Ezrin (EZR)
    Andere Bezeichnung
    Ezrin (EZR Produkte)
    Synonyme
    CVIL Protein, CVL Protein, VIL2 Protein, ezr Protein, vil2 Protein, wu:fc05c03 Protein, wu:fj31d06 Protein, cvil Protein, cvl Protein, Vil2 Protein, AW146364 Protein, R75297 Protein, p81 Protein, ezr.S Protein, ezrin Protein, ezrin b Protein, ezrin L homeolog Protein, EZR Protein, ezrb Protein, ezr Protein, Ezr Protein, ezr.L Protein
    Hintergrund
    The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
    Molekulargewicht
    69.2 kDa
    NCBI Accession
    NP_003370
    Pathways
    Maintenance of Protein Location
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