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EZH2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

EZH2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2720645
  • Target Alle EZH2 Proteine anzeigen
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 6
    • 1
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses EZH2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human EZH2 / KMT6 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product EZH2 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Pedram Fatemi, Salah-Uddin, Modarresi, Khoury, Wahlestedt, Faghihi: "Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen." in: Journal of biomolecular screening, Vol. 20, Issue 9, pp. 1132-41, (2015) (PubMed).

    Tushir, Akbarian: "Chromatin-bound RNA and the neurobiology of psychiatric disease." in: Neuroscience, Vol. 264, pp. 131-41, (2014) (PubMed).

  • Target
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    Andere Bezeichnung
    Ezh2,kmt6 (EZH2 Produkte)
    Synonyme
    ENX-1 Protein, ENX1 Protein, EZH1 Protein, EZH2b Protein, KMT6 Protein, KMT6A Protein, WVS Protein, WVS2 Protein, eya2 Protein, im:7149338 Protein, zgc:136376 Protein, zgc:152758 Protein, EZH2 Protein, enx-1 Protein, enx1 Protein, ezh1 Protein, kmt6 Protein, xez Protein, Enx-1 Protein, Enx1h Protein, mKIAA4065 Protein, ezh2 Protein, olezh2 Protein, enhancer of zeste 2 polycomb repressive complex 2 subunit Protein, enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog Protein, enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog Protein, EZH2 Protein, ezh2 Protein, Ezh2 Protein, ezh2.L Protein, ezh2.S Protein
    Hintergrund
    This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
    Molekulargewicht
    85.8 kDa
    NCBI Accession
    NP_004447
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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