EDARADD Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719929

Produktdetails

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant B

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses EDARADD Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human EDARADD (transcript variant B) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Andere Bezeichnung: Edaradd (EDARADD Produkte)

Synonyme: 1810032E07Rik Protein, 5830469M23Rik Protein, A630043P06 Protein, cr Protein, ECTD11A Protein, ECTD11B Protein, ED3 Protein, EDA3 Protein, EDAR (ectodysplasin-A receptor)-associated death domain Protein, EDAR associated death domain Protein, Edaradd Protein, EDARADD Protein

Hintergrund: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Molekulargewicht: 23.5 kDa

NCBI Accession: NP_542776

Pathways: Ubiquitin Proteasome Pathway