DNM2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719861

Produktdetails

Target: DNM2 (Dynamin 2 (DNM2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DNM2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Dynamin-2 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: DNM2 (Dynamin 2 (DNM2))

Andere Bezeichnung: Dynamin-2 (DNM2 Produkte)

Synonyme: dynamin-2 Protein, cmtdi1 Protein, cmtdib Protein, dyn2 Protein, dynII Protein, CMT2M Protein, CMTDI1 Protein, CMTDIB Protein, DI-CMTB Protein, DYN2 Protein, DYNII Protein, LCCS5 Protein, Dyn2 Protein, Udnm Protein, DYIIAAB Protein, dnm2 Protein, zgc:114072 Protein, dynamin 2 Protein, dynamin 2 L homeolog Protein, dynamin 2a Protein, dynamin 2-like Protein, DNM2 Protein, dnm2 Protein, dnm2.L Protein, Dnm2 Protein, dnm2a Protein, DNM2L Protein

Hintergrund: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

Molekulargewicht: 97.5 kDa

NCBI Accession: NP_004936

Pathways: Toll-Like Receptors Cascades