DUSP5 Protein (His tag)

Produktnummer ABIN2719839

Produktdetails

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses DUSP5 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human DUSP5 (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Andere Bezeichnung: Dusp5 (DUSP5 Produkte)

Synonyme: DUSP5 Protein, wu:fc03b11 Protein, wu:fc86e02 Protein, MGC84792 Protein, dusp Protein, hvh3 Protein, DUSP Protein, HVH3 Protein, Cpg21 Protein, Gm337 Protein, dual specificity phosphatase 5 Protein, dual specificity phosphatase 5 S homeolog Protein, DUSP5 Protein, dusp5 Protein, dusp5.S Protein, Dusp5 Protein

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

Molekulargewicht: 41.9 kDa

NCBI Accession: NP_004410