DUSP11 Protein (His tag)

Produktnummer ABIN2719826

Produktdetails

Target: DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses DUSP11 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human DUSP11 (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris, 8M Urea, pH 8.0.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))

Andere Bezeichnung: Dusp11 (DUSP11 Produkte)

Synonyme: pir1 Protein, DUSP11 Protein, 2010300F21Rik Protein, AI481497 Protein, wu:fa05e01 Protein, wu:fc09a06 Protein, wu:fk47e10 Protein, zgc:112166 Protein, PIR1 Protein, dusp11 Protein, dual specificity phosphatase 11 Protein, dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) Protein, dual specificity phosphatase 11 L homeolog Protein, DUSP11 Protein, DUSP11RC1I Protein, dusp11 Protein, Dusp11 Protein, dusp11.L Protein

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.

Molekulargewicht: 38.8 kDa

NCBI Accession: NP_003575