c-MYC Protein (His tag)

Produktnummer ABIN2715371

Produktdetails

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses c-MYC Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human c-Myc (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Andere Bezeichnung: C-Myc (MYC Produkte)

Synonyme: MRTL Protein, MYCC Protein, bHLHe39 Protein, c-Myc Protein, CMYC Protein, c-myc Protein, C-MYC Protein, LOC100136746 Protein, ARC Protein, B430311C09Rik Protein, MYC Protein, NOP Protein, Nop30 Protein, RNCMYC Protein, mMyc Protein, AU016757 Protein, Myc2 Protein, Niard Protein, Nird Protein, cmyc Protein, zc-myc Protein, c-myc II Protein, myc-B Protein, myc2 Protein, myc1 Protein, CMyc Protein, zgc:55680 Protein, CG10798 Protein, D-Myc Protein, DM Protein, DMYc Protein, Dm Protein, Dmel\CG10798 Protein, Dmyc Protein, EG:BACN5I9.1 Protein, anon-WO03040301.171 Protein, bHLHe57 Protein, c-MYC Protein, d-myc Protein, dMYC Protein, dMyc Protein, dMyc1 Protein, da Protein, dm Protein, dm/dMyc Protein, dm/myc Protein, dmyc Protein, dmyc1 Protein, l(1)G0139 Protein, l(1)G0354 Protein, l(1)G0359 Protein, myc Protein, MYC proto-oncogene, bHLH transcription factor Protein, v-myc myelocytomatosis viral oncogene homolog Protein, nucleolar protein 3 (apoptosis repressor with CARD domain) Protein, myelocytomatosis oncogene Protein, MYC proto-oncogene, bHLH transcription factor a Protein, MYC proto-oncogene, bHLH transcription factor L homeolog Protein, MYC proto-oncogene, bHLH transcription factor S homeolog Protein, v-myc myelocytomatosis viral oncogene homolog (avian) Protein, MYC proto-oncogene, bHLH transcription factor b Protein, CG10798 gene product from transcript CG10798-RB Protein, MYC Protein, LOC100136746 Protein, Nol3 Protein, Myc Protein, myca Protein, myc.L Protein, myc.S Protein, mycb Protein

Hintergrund: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Molekulargewicht: 48.8 kDa

NCBI Accession: NP_002458

Pathways: p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt