BCL11A Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2715190

Produktdetails

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BCL11A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Bcl-11A (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Andere Bezeichnung: Bcl-11a (BCL11A Produkte)

Synonyme: 2810047E18Rik Protein, BCL-11A Protein, Ctip1 Protein, D930021L15Rik Protein, Evi9 Protein, Evi9a Protein, Evi9b Protein, Evi9c Protein, mKIAA1809 Protein, BCL11A-L Protein, BCL11A-S Protein, BCL11A-XL Protein, BCL11a-M Protein, CTIP1 Protein, EVI9 Protein, HBFQTL5 Protein, ZNF856 Protein, bcl11a Protein, wu:fi09f10 Protein, zgc:136898 Protein, B cell CLL/lymphoma 11A (zinc finger protein) Protein, B-cell CLL/lymphoma 11A Protein, B-cell CLL/lymphoma 11A L homeolog Protein, B-cell CLL/lymphoma 11Aa Protein, Bcl11a Protein, BCL11A Protein, bcl11a.L Protein, bcl11aa Protein

Hintergrund: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Molekulargewicht: 26.7 kDa

NCBI Accession: NP_612569

Pathways: Regulation of Cell Size