ARFGAP3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714863

Produktdetails

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ARFGAP3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ARFGAP3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Andere Bezeichnung: Arfgap3 (ARFGAP3 Produkte)

Synonyme: ARFGAP1 Protein, 0610009H19Rik Protein, 1810004P07Rik Protein, 1810035F16Rik Protein, 9130416J18Rik Protein, Arfgap1 Protein, arfgap1 Protein, xgap Protein, zgc:85765 Protein, arfgap3 Protein, ADP ribosylation factor GTPase activating protein 3 Protein, ADP-ribosylation factor GTPase activating protein 3 Protein, ADP ribosylation factor GTPase activating protein 3 S homeolog Protein, ARFGAP3 Protein, Arfgap3 Protein, arfgap3 Protein, arfgap3.S Protein

Hintergrund: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.

Molekulargewicht: 56.7 kDa

NCBI Accession: NP_055385