EPS15 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714444

Produktdetails

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses EPS15 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human AF1P / EPS15 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Andere Bezeichnung: Af1p,eps15 (EPS15 Produkte)

Synonyme: AF-1P Protein, AF1P Protein, MLLT5 Protein, CG16932 Protein, Dmel\\CG16932 Protein, EH1 Protein, EPS-15 Protein, Eps15 Protein, anon-WO0118547.85 Protein, eps-15 Protein, eps15 Protein, i31 Protein, 2410112D09Rik Protein, RGD1307641 Protein, epidermal growth factor receptor pathway substrate 15 Protein, Epidermal growth factor receptor pathway substrate clone 15 Protein, hypothetical protein Protein, EPS15 Protein, Eps-15 Protein, eps15 Protein, Eps15 Protein, PGTG_06574 Protein

Hintergrund: This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 98.5 kDa

NCBI Accession: NP_001972

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation