ABHD12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714272

Produktdetails

Target: ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ABHD12 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ABHD12 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))

Andere Bezeichnung: Abhd12 (ABHD12 Produkte)

Synonyme: ABHD12 Protein, 1500011G07Rik Protein, 6330583M11Rik Protein, AI431047 Protein, AW547313 Protein, ABHD12A Protein, BEM46L2 Protein, C20orf22 Protein, PHARC Protein, dJ965G21.2 Protein, abhydrolase domain containing 12 Protein, abhydrolase domain containing 12 S homeolog Protein, ABHD12 Protein, CC1G_02966 Protein, PTRG_02160 Protein, abhd12.S Protein, Abhd12 Protein

Hintergrund: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011].

Molekulargewicht: 44.9 kDa

NCBI Accession: NP_001035937