ABAT Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714259

Produktdetails

Target: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ABAT Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ABAT (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Andere Bezeichnung: Abat (ABAT Produkte)

Synonyme: cb880 Protein, fj82a01 Protein, wu:fj82a01 Protein, BA0325 Protein, PSPTO0259 Protein, PSPTO0301 Protein, PSPTO1890 Protein, GABA-AT Protein, GABAT Protein, NPD009 Protein, GABA-T Protein, L-AIBAT Protein, 9630038C02Rik Protein, AI255750 Protein, ENSMUSG00000051226 Protein, Gabaat Protein, Gabat Protein, Gm9851 Protein, I54 Protein, Laibat Protein, X61497 Protein, beta-AlaAT Protein, 4-aminobutyrate aminotransferase Protein, 4-aminobutyrate--2-oxoglutarate transaminase Protein, GABA aminotransferase PLP-dependent PuuE Protein, 4-aminobutyrate aminotransferase, mitochondrial Protein, aspartate aminotransferase family protein Protein, 4-aminobutyrate aminotransferase S homeolog Protein, ABAT Protein, abat Protein, gabT Protein, puuE Protein, gabT-1 Protein, gabT-2 Protein, gabT-3 Protein, CNE01830 Protein, Mmwyl1_0047 Protein, CpipJ_CPIJ008729 Protein, KCR_RS04555 Protein, Bcenmc03_4909 Protein, Hden_0972 Protein, Dbac_2000 Protein, Mesil_2400 Protein, Trad_0121 Protein, abat.S Protein, Abat Protein

Hintergrund: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Molekulargewicht: 53.2 kDa

NCBI Accession: NP_000654

Pathways: Monocarboxylic Acid Catabolic Process