Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HOGA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

HOGA1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714034
  • Target Alle HOGA1 Proteine anzeigen
    HOGA1 (4-Hydroxy-2-Oxoglutarate Aldolase 1 (HOGA1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses HOGA1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Chromosome 10 open reading frame 65 (C10orf65), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HOGA1 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    HOGA1 (4-Hydroxy-2-Oxoglutarate Aldolase 1 (HOGA1))
    Andere Bezeichnung
    Chromosome 10 Open Reading Frame 65 (c10orf65) (HOGA1 Produkte)
    Synonyme
    C10orf65 Protein, DHDPS2 Protein, DHDPSL Protein, HP3 Protein, NPL2 Protein, 0610010D20Rik Protein, Dhdpsl Protein, Npl2 Protein, 4-hydroxy-2-oxoglutarate aldolase 1 Protein, HOGA1 Protein, Hoga1 Protein
    Hintergrund
    The authors of PMID:20797690 cloned this gene while searching for genes in a region of chromosome 10 linked to primary hyperoxalurea type III. They noted that even though the encoded protein has been described as a mitochondrial dihydrodipicolinate synthase-like enzyme, it shares little homology with E. coli dihydrodipicolinate synthase (Dhdps), particularly in the putative substrate-binding region. Moreover, neither lysine biosynthesis nor sialic acid metabolism, for which Dhdps is responsible, occurs in vertebrate mitochondria. They propose that this gene encodes mitochondrial 4-hydroxyl-2-oxoglutarate aldolase (EC 4.1.3.16), which catalyzes the final step in the metabolic pathway of hydroxyproline, releasing glyoxylate and pyruvate. This gene is predominantly expressed in the liver and kidney, and mutations in this gene are found in patients with primary hyperoxalurea type III. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
    Molekulargewicht
    35.1 kDa
    NCBI Accession
    NP_612422
    Pathways
    Monocarboxylic Acid Catabolic Process
Sie sind hier:
Kundenservice