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Chitotriosidase 1 Protein (His tag)

CHIT1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2713977
  • Target Alle Chitotriosidase 1 (CHIT1) Proteine anzeigen
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    Protein-Typ
    Recombinant
    Spezies
    • 8
    • 2
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Chitotriosidase 1 Protein ist gelabelt mit His tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Chitinase 1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product CHIT1 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the N-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    20 mM Tris-HCl, 150 mM NaCl, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    Andere Bezeichnung
    Chitinase 1 (CHIT1 Produkte)
    Synonyme
    CHI3 Protein, CHIT Protein, CHITD Protein, CHIT1 Protein, chio Protein, 2300002L19Rik Protein, chitinase 1 Protein, chitinase 1 (chitotriosidase) Protein, CHIT1 Protein, chit1 Protein, Chit1 Protein
    Hintergrund
    Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
    Molekulargewicht
    50.4 kDa
    NCBI Accession
    NP_003456
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