CENPA Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713904

Produktdetails

Target: CENPA (Centromere Protein A (CENPA))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CENPA Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CENP-A (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CENPA (Centromere Protein A (CENPA))

Andere Bezeichnung: Cenp-A (CENPA Produkte)

Synonyme: CENP-A Protein, CenH3 Protein, Cenp-A Protein, cenpx Protein, cenp-a Protein, sim2 Protein, Cenp-a Protein, RGD1563607 Protein, CENPA Protein, centromere protein A Protein, centromere protein-A Protein, centromeric histone-3 like protein Protein, centromere-specific histone H3 CENP-A Protein, cenp-A Protein, centromere protein A L homeolog Protein, histone H3-like centromeric protein A Protein, CENPA Protein, Cenpa Protein, CENP-A Protein, cenpa Protein, cenp-A Protein, cnp1 Protein, HAN_3g422 Protein, Cenp-a Protein, cenpa.L Protein, CMU_016480 Protein

Hintergrund: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 12.8 kDa

NCBI Accession: NP_001035891

Pathways: Chromatin Binding, Maintenance of Protein Location