CDKN2D Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713883

Produktdetails

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CDKN2D Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CDKN2D / p19INK4d (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Andere Bezeichnung: Cdkn2d,p19ink4d (CDKN2D Produkte)

Synonyme: ink4d Protein, p19 Protein, p19-ink4d Protein, CDKN2D Protein, ank2 Protein, INK4D Protein, p19-INK4D Protein, INK4d Protein, p19INK4d Protein, cyclin-dependent kinase inhibitor 2D S homeolog Protein, cyclin dependent kinase inhibitor 2D Protein, cyclin-dependent kinase inhibitor 2D Protein, Cyclin-dependent kinase 4 inhibitor D Protein, cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) Protein, similar to cyclin-dependent kinase inhibitor 2D Protein, cdkn2d.S Protein, CDKN2D Protein, cdkn2d Protein, cdn2d Protein, Cdkn2d Protein

Hintergrund: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Molekulargewicht: 17.5 kDa

NCBI Accession: NP_001791

Pathways: Zellzyklus, Sensory Perception of Sound, Mitotic G1-G1/S Phases, Negative Regulation of intrinsic apoptotic Signaling