CD247 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713537

Produktdetails

Target: CD247 (CD247 Molecule (CD247))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD247 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CD247 / CD3Z (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CD247 (CD247 Molecule (CD247))

Andere Bezeichnung: Cd247,cd3z (CD247 Produkte)

Synonyme: CD3-ZETA Protein, CD3H Protein, CD3Q Protein, CD3Z Protein, T3Z Protein, TCRZ Protein, 4930549J05Rik Protein, A430104F18Rik Protein, AW552088 Protein, Cd3 Protein, Cd3-eta Protein, Cd3-zeta Protein, Cd3h Protein, Cd3z Protein, Cd3zeta Protein, T3z Protein, Tcrk Protein, Tcrz Protein, LOC100136514 Protein, LOC100136549 Protein, LOC100305023 Protein, CD247 Protein, TCRzeta Protein, CD247 molecule Protein, CD247 antigen Protein, CD3zeta-2 Protein, CD3zeta-1 Protein, Cd247 molecule Protein, CD247 Protein, Cd247 Protein, cd3z Protein, cd247 Protein

Hintergrund: The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molekulargewicht: 16.2 kDa

NCBI Accession: NP_000725

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway