Calpain S1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713113

Produktdetails

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Calpain S1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CAPNS1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Andere Bezeichnung: Capns1 (CAPNS1 Produkte)

Synonyme: 30K Protein, CALPAIN4 Protein, CANP Protein, CANPS Protein, CAPN4 Protein, CDPS Protein, CSS1 Protein, Capn4 Protein, CAPNS1 Protein, Capa-4 Protein, Capa4 Protein, D7Ertd146e Protein, MGC84330 Protein, capns1 Protein, cb616 Protein, wu:fb81g08 Protein, wu:fl09e04 Protein, zgc:110603 Protein, calpain small subunit 1 Protein, calpain, small subunit 1 Protein, calpain, small subunit 1 L homeolog Protein, calpain, small subunit 1 a Protein, CAPNS1 Protein, Capns1 Protein, capns1.L Protein, capns1a Protein

Hintergrund: This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 28.1 kDa

NCBI Accession: NP_001740

Pathways: Apoptose