CAMKK2 Protein (Transcript Variant 7) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713099

Produktdetails

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 7

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CAMKK2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CAMKK2 (transcript variant 7) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Andere Bezeichnung: Camkk2 (CAMKK2 Produkte)

Synonyme: CAMKK Protein, CAMKKB Protein, 6330570N16Rik Protein, AW061083 Protein, mKIAA0787 Protein, camk2b Protein, fj90d04 Protein, wu:fj90d04 Protein, si:dkey-174n20.2 Protein, CAMKK2 Protein, calcium/calmodulin dependent protein kinase kinase 2 Protein, calcium/calmodulin-dependent protein kinase kinase 2, beta Protein, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 Protein, calcium/calmodulin dependent protein kinase II beta Protein, calcium/calmodulin-dependent protein kinase kinase 2 Protein, CAMKK2 Protein, Camkk2 Protein, camk2b1 Protein, CAMK2B Protein, camkk2 Protein

Hintergrund: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.

Molekulargewicht: 59.4 kDa

NCBI Accession: NP_757380

Pathways: AMPK Signaling