CACNA2D2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target Alle CACNA2D2 Proteine anzeigen
- CACNA2D2 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 3
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CACNA2D2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human CACNA2D2 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CACNA2D2 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CACNA2D2 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2))
- Andere Bezeichnung
- Cacna2d2 (CACNA2D2 Produkte)
- Synonyme
- CACNA2D Protein, LUAC11.1 Protein, Cacna2d Protein, a2d2 Protein, du Protein, mKIAA0558 Protein, td Protein, torpid Protein, calcium voltage-gated channel auxiliary subunit alpha2delta 2 Protein, calcium channel, voltage-dependent, alpha 2/delta subunit 2 Protein, CACNA2D2 Protein, Cacna2d2 Protein
- Hintergrund
- Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molekulargewicht
- 130.3
- NCBI Accession
- NP_001167522
- Pathways
- Skeletal Muscle Fiber Development
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