CYP46A1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712777

Produktdetails

Target: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CYP46A1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CYP46A1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Andere Bezeichnung: Cyp46a1 (CYP46A1 Produkte)

Synonyme: CP46 Protein, CYP46 Protein, CYP46A1 Protein, zgc:109896 Protein, MGC147389 Protein, Cyp46 Protein, cytochrome P450 family 46 subfamily A member 1 Protein, cytochrome P450 family 46 subfamily A member 1 L homeolog Protein, cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 Protein, cytochrome P450, family 46 Protein, cytochrome P450 46A1 Protein, cytochrome P450, family 46, subfamily a, polypeptide 1 Protein, cholesterol 24-hydroxylase Protein, cytochrome P450, family 46, subfamily A, polypeptide 1 Protein, CYP46A1 Protein, cyp46a1.L Protein, cyp46a1.1 Protein, cyp46a1 Protein, PTRG_08343 Protein, PTRG_09667 Protein, Cyp46a1 Protein, Sgly_1093 Protein

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Molekulargewicht: 56.6 kDa

NCBI Accession: NP_006659