CYP2C8 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712766

Produktdetails

Target: CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CYP2C8 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CYP2C8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Andere Bezeichnung: Cyp2c8 (CYP2C8 Produkte)

Synonyme: CPC8 Protein, CYPIIC8 Protein, MP-12/MP-20 Protein, CYP2C74 Protein, cpc8 Protein, cyp2c8 Protein, cypiic8 Protein, mp-12/mp-20 Protein, cytochrome P450 family 2 subfamily C member 8 Protein, Cytochrome P450 2C8 Protein, cytochrome P450, family 2, subfamily C, polypeptide 8 Protein, cytochrome P450 family 2 subfamily C member 8 S homeolog Protein, CYP2C8 Protein, CTN_0597 Protein, cyp2c8.1.S Protein, cyp2c8.1 Protein

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.

Molekulargewicht: 55.6 kDa

NCBI Accession: NP_000761