CYP1A2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712754

Produktdetails

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CYP1A2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CYP1A2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Andere Bezeichnung: Cyp1a2 (CYP1A2 Produkte)

Synonyme: CP12 Protein, P3-450 Protein, P450(PA) Protein, CYP1A2 Protein, CYPIA2 Protein, P450-PM4 Protein, Cyp1a1 Protein, P450-3 Protein, CYPD45 Protein, P-450d Protein, RATCYPD45 Protein, CYP1A5 Protein, CP450 Protein, CYP-IA2 Protein, cytochrome P450 family 1 subfamily A member 2 Protein, cytochrome P450 1A2 Protein, cytochrome P450 LM4 Protein, cytochrome P450, family 1, subfamily A, polypeptide 2 Protein, cytochrome P450, family 1, subfamily a, polypeptide 2 Protein, cytochrome P450 1A2-like Protein, CYP1A2 Protein, LOC100328937 Protein, Cyp1a2 Protein, VDBG_06455 Protein, LOC101825565 Protein, LOC102130662 Protein

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Molekulargewicht: 58.2 kDa

NCBI Accession: NP_000752