CTBP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712602

Produktdetails

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CTBP2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CTBP2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Boxer, Barajas, Tao, Zhang, Khavari: "ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes." in: Genes & development, Vol. 28, Issue 18, pp. 2013-26, (2014) (PubMed).

Antigendetails

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Andere Bezeichnung: Ctbp2 (CTBP2 Produkte)

Synonyme: ctbp Protein, ctbp-b Protein, xctbp Protein, AA407280 Protein, D7Ertd45e Protein, Gtrgeo6 Protein, Ribeye Protein, fe05b01 Protein, wu:fb96g03 Protein, wu:fe05b01 Protein, wu:fk19e02 Protein, C-terminal binding protein 2 Protein, C-terminal-binding protein 2 Protein, C-terminal binding protein 2a Protein, C-terminal binding protein 2 S homeolog Protein, ctbp2 Protein, LOC100398309 Protein, CTBP2 Protein, Ctbp2 Protein, ctbp2a Protein, ctbp2.S Protein

Hintergrund: This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3 however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.

Molekulargewicht: 48.8 kDa

NCBI Accession: NP_001320