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BPTF Protein (AA 2791-2911) (His tag,DYKDDDDK Tag)

BPTF Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Bind, ScA
Produktnummer ABIN2669695
  • Target Alle BPTF Produkte
    BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 2791-2911
    Spezies
    Human
    Quelle
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses BPTF Protein ist gelabelt mit His tag,DYKDDDDK Tag.
    Applikation
    Binding Studies (Bind), Screening Assay (ScA)
    Produktmerkmale
    The peptide corresponding to amino acids 2791-2911 that contains the bromodomain sequences of BPTF / FALZ (accession number NP_872579.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.3 kDa.
  • Applikationshinweise
    Recombinant BPTF / FALZ (2791-2911) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Handhabung
    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
  • Target
    BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))
    Andere Bezeichnung
    BPTF / FALZ (BPTF Produkte)
    Synonyme
    FAC1 Protein, FALZ Protein, NURF301 Protein, 9430093H17Rik Protein, Falz Protein, BPTF Protein, bromodomain PHD finger transcription factor Protein, nucleosome-remodeling factor subunit NURF301 Protein, fetal alzheimer antigen, falz Protein, BPTF Protein, Bptf Protein, LOC5576547 Protein, CpipJ_CPIJ011285 Protein, bptf Protein
    Hintergrund
    Bromodomain PHD finger transcription factor (BPTF), also known as Fetal Alzheimer antigen (FALZ), is a histone-binding component of NuRF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. BPTF protein contains a DNA-binding domain, a zinc finger motif and a bromodomain. Bromodomains recognize acetylated histone lysine residues and function as 'readers' of these epigenetic histone marks to regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. BPTF also specifically recognizes H3 tails trimethylated on lysine 4 (H3K4me3), which mark transcription start sites of virtually all active genes. It may also regulate transcription through direct binding to DNA or transcription factors.
    Molekulargewicht
    20.3 kDa
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