BRD1 Protein (AA 556-688) (His tag,DYKDDDDK Tag)

Produktnummer ABIN2669686

Produktdetails

Target: BRD1 (Bromodomain Containing 1 (BRD1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 556-688

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BRD1 Protein ist gelabelt mit His tag,DYKDDDDK Tag.

Applikation: Binding Studies (Bind), Screening Assay (ScA)

Produktmerkmale: The peptide corresponding to amino acids 556-688 that contains the bromodomain sequences of BRD1 (accession number NP_055392.1) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 21.5 kDa.

Anwendungsinformationen

Applikationshinweise: Recombinant BRD1 (556-688) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.

Antigendetails

Target: BRD1 (Bromodomain Containing 1 (BRD1))

Andere Bezeichnung: BRD1 (BRD1 Produkte)

Synonyme: BDNF Protein, MGC80898 Protein, BRD1 Protein, brd1 Protein, im:7138929 Protein, si:dkey-164m14.6 Protein, LOC733743 Protein, MGC146307 Protein, BRL Protein, BRPF1 Protein, BRPF2 Protein, 1110059H06Rik Protein, AI316859 Protein, mKIAA4191 Protein, bromodomain containing 1 Protein, bromodomain containing 1 L homeolog Protein, bromodomain containing 1a Protein, BRD1 Protein, brd1.L Protein, brd1a Protein, brd1 Protein, Brd1 Protein

Hintergrund: Bromodomain-containing protein 1 (BRD1) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of several members that function in the regulation of transcriptional activation and chromatin remodeling.

Molekulargewicht: 21.5 kDa