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Polybromo 1 Protein (PBRM1) (AA 613-734) (His tag,DYKDDDDK Tag)

PBRM1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant
Produktnummer ABIN2669650
  • Target Alle Polybromo 1 (PBRM1) Proteine anzeigen
    Polybromo 1 (PBRM1)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 613-734
    Spezies
    • 5
    • 1
    Human
    Quelle
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses Polybromo 1 Protein ist gelabelt mit His tag,DYKDDDDK Tag.
    Produktmerkmale
    The peptide corresponding to amino acids 613 - 734 that contains the bromodomain sequences of PBRM1 (accession number NP_060635.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.513 kDa. It shows binding specificity for acetylated H3K14.
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    Discover our top product PBRM1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Handhabung
    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
  • Target
    Polybromo 1 (PBRM1)
    Andere Bezeichnung
    PBRM1 (PBRM1 Produkte)
    Synonyme
    pb1 Protein, BAF180 Protein, PB1 Protein, 2610016F04Rik Protein, AI507524 Protein, Pb1 Protein, RGD1565549 Protein, polybromo 1 Protein, polybromo 1 L homeolog Protein, protein polybromo-1 Protein, PBRM1 Protein, pbrm1.L Protein, LOC100170602 Protein, pbrm1 Protein, Pbrm1 Protein
    Hintergrund
    Polybromo 1 (PBRM1) protein, also known as BRG1-associated factor 180 (BAF180) is the chromatin targeting subunit of the SWI/SNF-B (PBAF) chromatin remodeling complex that is involved in transcriptional activation and repression of select genes. PBRM1 targets chromatin via its six bromodomains that recognize and bind acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. PBRM1 also acts as an inhibitor of cell proliferation and demonstrates tumor suppressing properties in relation to breast, liver and lung cancers.
    Molekulargewicht
    20.513 kDa
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