BRPF1
(Bromodomain and PHD Finger Containing, 1 (BRPF1))
Protein-Typ
Recombinant
Proteineigenschaft
AA 627-746
Spezies
Human
Quelle
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses BRPF1 Protein ist gelabelt mit His tag,DYKDDDDK Tag.
Applikation
Binding Studies (Bind), Screening Assay (ScA)
Produktmerkmale
The peptide corresponding to amino acids 627 - 746 that contains the bromodomain sequences of BRPF1 (accession number NM_001003694.1) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.3 kDa.
Crystallography grade
BRPF1
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, WB, Crys, SDS
Applikationshinweise
Recombinant BRPF1 (627-746) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Lagerung
-80 °C
Informationen zur Lagerung
Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
Target
BRPF1
(Bromodomain and PHD Finger Containing, 1 (BRPF1))
Bromodomain and PHD finger containing (BRPF1) protein is a component of the MOZ/MORF complex which has histone H3 acetyltransferase activity. The bromodomain of BRPF1 recognizes acetylated histone lysine residues and function as a 'reader' of these epigenetic histone marks to regulate chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. BRPF1 is known to positively regulate the transcription of RUNX1 and RUNX2.