MTCH2 Protein (AA 29-174) (His tag)

Produktnummer ABIN2468870

Produktdetails

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 29-174

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MTCH2 Protein ist gelabelt mit His tag.

Applikation: Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)

Reinheit: ~95 %

Anwendungsinformationen

Applikationshinweise: This recombinant protein can be used for WB, ELISA, MS and neutralization assays.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1X PBS containing 0.1 % SDS

Handhabung: Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Lagerung: -80 °C

Informationen zur Lagerung: Store in working aliquots at -70 °C.

Antigendetails

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Andere Bezeichnung: MTCH2 (MTCH2 Produkte)

Synonyme: MIMP Protein, SLC25A50 Protein, Hspc032 Protein, fi20c06 Protein, fj35g12 Protein, wu:fi20c06 Protein, wu:fj35g12 Protein, 2310034D24Rik Protein, 4930539J07Rik Protein, HSPC032 Protein, mitochondrial carrier 2 Protein, mitochondrial carrier 2 L homeolog Protein, mitochondrial carrier homolog 2 Protein, MTCH2 Protein, mtch2.L Protein, Mtch2 Protein, mtch2 Protein

Hintergrund: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals (4-6), suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. The doublet observed in the SDS-PAGE is likely due to incomplete removal of the signal sequence.

Molekulargewicht: 19 kDa (Calculated)

Gen-ID: 56428

NCBI Accession: NP_055157

OMIM: 5815347

UniProt: Q791V5