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GLP-1 Protein

GLP-1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant < 98 % by SDS-PAGE gel and HPLC analyses.
Produktnummer ABIN2468485
  • Target Alle GLP-1 Proteine anzeigen
    GLP-1 (Glucagon-like peptide 1 (GLP-1))
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 3
    Escherichia coli (E. coli)
    Sequenz
    HAEGTFTSDV SSYLEGQAAK EFIAWLVKGR G
    Reinheit
    < 98 % by SDS-PAGE gel and HPLC analyses.
    Endotoxin-Niveau
    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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    Discover our top product GLP-1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Handhabung
    As with any protein, exposing GLP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
    Haltbarkeit
    24 months
  • Target
    GLP-1 (Glucagon-like peptide 1 (GLP-1))
    Andere Bezeichnung
    GLP-1 (GLP-1 Produkte)
    Synonyme
    GLP1 Protein, GLP2 Protein, GRPP Protein, GLP-1 Protein, Glu Protein, PPG Protein, glucagon Protein, GCG Protein, Gcg Protein
    Hintergrund
    GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic beta-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
    Gen-ID
    2641
    NCBI Accession
    NP_002045
    OMIM
    4503945
    UniProt
    P01275
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