Endonuclease G Protein (ENDOG) (AA 51-140) (His tag,Strep II tag)
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- Target Alle Endonuclease G (ENDOG) Proteine anzeigen
- Endonuclease G (ENDOG)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 51-140
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Endonuclease G Protein ist gelabelt mit His tag,Strep II tag.
- Applikation
- Western Blotting (WB), ELISA, Mass Spectrometry (MS)
- Reinheit
- ~95 %
- Top Product
- Discover our top product ENDOG Protein
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Endonuclease G (ENDOG) (AA 23-212) protein (His-IF2DI Tag)
ENDOG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Endonuclease G (ENDOG) (AA 50-297) protein (GST tag)ENDOG Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Endonuclease G (ENDOG) (AA 49-297) protein (His tag)Crystallography grade ENDOG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endonuclease G (ENDOG) (AA 45-294) protein (His tag)Crystallography grade ENDOG Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endonuclease G (ENDOG) (AA 1-294) (Active) protein (His tag,GST tag)ENDOG Spezies: Ratte Wirt: Escherichia coli (E. coli) > 90 % AcA, CC Active
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- Applikationshinweise
- This recombinant protein can be used for WB, ELISA, MS.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 1X PBS containing 0.1 % SDS and 0.02 % NaN
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store in working aliquots at -70 °C.
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- Target
- Endonuclease G (ENDOG)
- Andere Bezeichnung
- EndoG (ENDOG Produkte)
- Synonyme
- CG8862 Protein, Dmel\\CG8862 Protein, Tb08.10J17.140 Protein, Tb08.10J17.90 Protein, TBC1D13 Protein, endog Protein, ENDOG Protein, wu:fb79c08 Protein, zgc:110020 Protein, Endonuclease G Protein, endonuclease G Protein, putative endonuclease G Protein, endonuclease G, mitochondrial Protein, endonuclease G L homeolog Protein, EndoG Protein, Tc00.1047053506867.10 Protein, Tb927.8.4040 Protein, Tb927.8.4090 Protein, LBRM_10_0750 Protein, LMJF_10_0610 Protein, NAEGRDRAFT_78507 Protein, ENDOG Protein, endog Protein, eNDOG Protein, LOC100529218 Protein, Endog Protein, endog.L Protein
- Hintergrund
- The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribo-nuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (EndoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD (1-3). EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans (2). EndoG also cleaves DNA in vitro (4).
- Molekulargewicht
- 15 kDa (Calculated)
- Gen-ID
- 2021
- OMIM
- 24638471
- UniProt
- Q14249
- Pathways
- Apoptose
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