TNFRSF12A
(Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
Protein-Typ
Recombinant
Proteineigenschaft
AA 28-79
Spezies
Human
Quelle
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses TNFRSF12A Protein ist gelabelt mit Fc Tag.
Sequenz
AA 28-79
Produktmerkmale
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 33 kDa. As a result of glycosylation, the protein migrates as 32-40 kDa under reducing (R) condition, and 65-80 kDa under non-reducing (NR) condition (SDS-PAGE).
TNFRSF12A
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
Crystallography grade
TNFRSF12A
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
WB, SDS, ELISA, Crys
TNFRSF12A
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
50 mM Tris, 100 mM Glycine, pH 7.5
Handhabung
Please avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Target
TNFRSF12A
(Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14 (FN14 or FGF-inducible 14), Tweak-receptor, CD antigen CD266. TNFRSF12A contains one TNFR-Cys repeat. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A is receptor for TNFSF12/TWEAK, and is weak inducer of apoptosis in some cell types. TNFRSF12A / FN14 promotes angiogenesis and the proliferation of endothelial cells.