IFNAR2 Protein (AA 27-243) (His tag)
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- Target Alle IFNAR2 Proteine anzeigen
- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 27-243
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IFNAR2 Protein ist gelabelt mit His tag.
- Sequenz
- AA 27-243
- Produktmerkmale
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.6 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
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Interferon alpha/beta Receptor 2 (IFNAR2) (AA 27-243) protein (His tag)Crystallography grade IFNAR2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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Interferon alpha/beta Receptor 2 (IFNAR2) (AA 27-515) protein (rho-1D4 tag)Crystallography grade IFNAR2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 22-513) protein (rho-1D4 tag)Crystallography grade IFNAR2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
- Andere Bezeichnung
- IFNAR2 (IFNAR2 Produkte)
- Synonyme
- AI747302 Protein, Ifnar-2 Protein, IFN-R Protein, IFN-alpha-REC Protein, IFNABR Protein, IFNARB Protein, IFN-R-2 Protein, IFNBR Protein, interferon alpha and beta receptor subunit 2 Protein, interferon (alpha and beta) receptor 2 Protein, IFNAR2 Protein, Ifnar2 Protein
- Hintergrund
- Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection.
- Molekulargewicht
- 25.8 kDa
- NCBI Accession
- NP_997467
- Pathways
- JAK-STAT Signalweg, Hepatitis C
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