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Hemagglutinin (HA) (AA 19-338), (AA 341-523) protein (His tag) Protein

HA Spezies: Influenza Virus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Pubmed (2 Referenzen)
Produktnummer ABIN2181202
$286.00
Zzgl. Versandkosten $45.00
Lieferung in 16 bis 41 Werktagen
  • Target Alle Hemagglutinin (HA) Proteine anzeigen
    Hemagglutinin (HA)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 19-338, AA 341-523
    Spezies
    • 16
    • 11
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Influenza Virus
    Virus Strain
    A/Shanghai/2/2013
    Quelle
    • 71
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Hemagglutinin Protein ist gelabelt mit His tag.
    Sequenz
    AA 19-338,AA 341-523
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.6 kDa. The protein migrates as 63-75 kDa under reducing (R) condition (SDS-PAGE).
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Liu, Yang, Yuan, Liao, Duan, Wang, Zhang, Chen, Zhou: "Early Antibody Response Contributes to the Virus Eradication and Clinical Recovery of H7N9 Influenza Infection." in: Annals of clinical and laboratory science, Vol. 47, Issue 5, pp. 592-599, (2018) (PubMed).

    Zhang, Gu, Ouyang, Xie: "Proinflammatory effects of the hemagglutinin protein of the avian influenza A (H7N9) virus and microRNA‑mediated homeostasis response in THP‑1 cells." in: Molecular medicine reports, Vol. 12, Issue 4, pp. 6241-6, (2016) (PubMed).

  • Target
    Hemagglutinin (HA)
    Abstract
    HA Produkte
    Synonyme
    hemagglutinin, Hemagglutinin, HA, HA, ha
    Substanzklasse
    Influenza Protein
    Hintergrund
    Influenza, commonly known as "the flu", is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease. The serotypes that have been confirmed in humans, ordered by the number of known human pandemic deaths, are: H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, H10N7, H7N9. H7N9 is a serotype of the species Influenzavirus A (avian influenza virus or bird flu virus). H7 normally circulates amongst avian populations with some variants known to occasionally infect humans. An H7N9 virus was first reported to have infected humans in 2013 in China.
    Molekulargewicht
    56.7 kDa
    Gen-ID
    18, 17
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